TMEM132C

Across TCGA pan-cancer cohorts, TMEM132C mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TMEM132C data layer compared with 29 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TMEM132C mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TMEM132C expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

OV and UCEC are the cancer types where TMEM132C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Quartile	All	0.923	0.579	.024	4	view →
UCEC	DFS	Median	All	0.703	0.926	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TMEM132C–OV (DFS)

Open the OV breakdown →