TMEM132C

Across TCGA cell cohorts, TMEM132C RNA expression is significantly associated with the go_rna of many other GO terms, with 371 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TMEM132C-associated GO terms across cancer lineages are Positive regulation of cyclase activity, Purine nucleoside triphosphate metabolic process, and Regulation of calcium ion transport into cytosol. Each is linked with TMEM132C in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM132C-to-partner and partner-to-TMEM132C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cyclase activity grouped by TMEM132C-low versus TMEM132C-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132C→partner) and Y-score (partner→TMEM132C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of cyclase activity →	-0.100	-1.839	<.001	.007	2	4
LUNG_SCLC	Purine nucleoside triphosphate metabolic process →	+0.060	+0.894	.002	.004	3	3
LUNG_SCLC	Regulation of calcium ion transport into cytosol →	-0.199	-1.032	<.001	.004	3	3
LUNG_SCLC	Cytosolic small ribosomal subunit assembly →	+0.054	+0.838	.001	.003	3	3
LUNG_SCLC	Regulation of metaphase/anaphase transition of cell cycle →	+0.065	+1.127	<.001	.002	3	3
LUNG_SCLC	Regulation of mitotic metaphase/anaphase transition →	+0.069	+1.135	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

Positive regulation of cyclase activity by TMEM132C expression — SOFT_TISSUE

Explore this box plot interactively →