TMEM132C

Across TCGA cell cohorts, TMEM132C mutation is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM132C-associated genes across cancer lineages are AGL, TBL1Y, and OR9A4. Each is linked with TMEM132C in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM132C-to-partner and partner-to-TMEM132C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGL grouped by TMEM132C-low versus TMEM132C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132C→partner) and Y-score (partner→TMEM132C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AGL →	+0.930	+3.212	<.001	.006	3	3
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	2
SOFT_TISSUE	OR9A4 →	+0.022	+4.369	<.001	.008	3	2
LUNG_SCLC	ASPHD2 →	+0.655	+2.459	.002	.003	3	2
LARGE_INTESTINE	RPS9 →	+0.592	+3.212	<.001	.006	3	2
BLOOD_Leukemia	GLMN →	+0.635	+3.199	.002	.007	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

AGL by TMEM132C expression — LARGE_INTESTINE

Explore this box plot interactively →