TMEM132B

Across TCGA patient cohorts, TMEM132B protein abundance is significantly associated with the RNA expression of many other genes, with 7,002 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM132B-associated genes across cancer lineages are YPEL1, SNRPD3, and MAPK1. Each is linked with TMEM132B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM132B-to-partner and partner-to-TMEM132B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM132B versus YPEL1 in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132B→partner) and Y-score (partner→TMEM132B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.421	+0.427	.001	<.001	3	1
GBM	SNRPD3 →	+0.413	+0.581	<.001	<.001	3	1
GBM	MAPK1 →	+0.437	+0.545	<.001	.003	3	1
GBM	GGT1 →	+0.175	+0.634	.001	<.001	3	1
GBM	ESS2 →	+0.299	+0.484	.002	.003	3	1
GBM	SEZ6L →	+1.618	+0.640	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,002 associations by consensus.

TMEM132B vs YPEL1 — GBM

Explore this scatter interactively →