TMEM130

Across TCGA patient cohorts, TMEM130 protein abundance is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM130-associated genes across cancer lineages are FKBP3, FGL1, and PDE4C. Each is linked with TMEM130 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM130-to-partner and partner-to-TMEM130 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM130 versus FKBP3 in LUAD, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM130→partner) and Y-score (partner→TMEM130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FKBP3 →	+0.702	+1.400	.007	.006	3	1
LUAD	FGL1 →	+4.519	+1.400	.001	.006	3	1
LUAD	PDE4C →	-0.226	-1.420	.002	.005	3	1
LUAD	PSMA1 →	+0.377	+1.400	<.001	.006	3	1
LUAD	GCH1 →	+1.035	+1.400	.002	.006	3	1
LUAD	ZFP37 →	+0.716	+1.839	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

TMEM130 vs FKBP3 — LUAD

Explore this scatter interactively →