TMEM129

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TMEM129 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TMEM129 data layer compared with 23 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher TMEM129 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM129 expression acts as an unfavorable survival marker.

STAD are the cancer types where TMEM129 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianAll0.1840.730.00133view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

TMEM129–STAD (OS)

Kaplan–Meier survival curve for TMEM129 mutant vs wild-type samples in STAD.

Open the STAD breakdown →

Exploration