TMEM129

Across TCGA patient cohorts, TMEM129 protein abundance is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM129-associated genes across cancer lineages are LATS1, TAF4B, and LINC02245. Each is linked with TMEM129 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM129-to-partner and partner-to-TMEM129 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM129 versus LATS1 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM129→partner) and Y-score (partner→TMEM129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LATS1 →	-0.475	-0.283	.001	.005	3	2
LSCC	TAF4B →	-0.796	-0.385	<.001	<.001	3	2
LSCC	LINC02245 →	-0.330	-0.295	.001	<.001	3	2
CCRCC	PCDHB8 →	+0.903	+0.418	<.001	.001	3	2
HNSC	NECTIN3 →	+1.028	+0.501	.006	.001	3	2
LUAD	DNAL4 →	+0.396	+0.237	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

TMEM129 vs LATS1 — LSCC

Explore this scatter interactively →