TMEM128

Across TCGA cell cohorts, TMEM128 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,127 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM128-associated GO terms across cancer lineages are Positive regulation of bone development, Endoplasmic reticulum mannose trimming, and Glucosamine metabolic process. Each is linked with TMEM128 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM128-to-partner and partner-to-TMEM128 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of bone development grouped by TMEM128-low versus TMEM128-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM128→partner) and Y-score (partner→TMEM128) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of bone development →	+1.080	+1.060	<.001	<.001	3	12
URINARY_TRACT	Endoplasmic reticulum mannose trimming →	+0.160	+1.150	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Glucosamine metabolic process →	+0.158	+0.854	.001	.001	3	9
URINARY_TRACT	Vesicle targeting, rough ER to cis-Golgi →	+0.089	+0.773	<.001	.003	3	9
LIVER	Vesicle budding from membrane →	+0.087	+0.776	.005	.006	3	9
BLOOD_Myeloma	Golgi organization →	+0.055	+0.995	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,127 associations by consensus.

Positive regulation of bone development by TMEM128 expression — PANCREAS

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