TMEM127

Across TCGA cell cohorts, TMEM127 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,223 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM127-associated GO terms across cancer lineages are Endosomal transport, Vacuolar transport, and Macroautophagy. Each is linked with TMEM127 in more than 18 cancer types. Because this analysis shows association rather than direction, both TMEM127-to-partner and partner-to-TMEM127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by TMEM127-low versus TMEM127-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM127→partner) and Y-score (partner→TMEM127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endosomal transport →	+0.062	+0.924	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.064	+0.946	<.001	<.001	3	19
KIDNEY	Macroautophagy →	+0.068	+1.044	.003	.003	3	18
BONE	Post-Golgi vesicle-mediated transport →	+0.076	+1.043	.001	.001	3	18
BONE	Vacuole organization →	+0.070	+1.309	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Establishment of protein localization to vacuole →	+0.089	+0.860	.002	.005	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,223 associations by consensus.

Endosomal transport by TMEM127 expression — OESOPHAGUS

Explore this box plot interactively →