TMEM127

Across TCGA cell cohorts, TMEM127 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM127-associated genes across cancer lineages are KRTAP2-1 and PSG11. Each is linked with TMEM127 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM127-to-partner and partner-to-TMEM127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP2-1 grouped by TMEM127-low versus TMEM127-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM127→partner) and Y-score (partner→TMEM127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP2-1 →	+0.064	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	PSG11 →	+0.097	+4.714	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP2-1 by TMEM127 expression — BLOOD_Lymphoma

Explore this box plot interactively →