TMEM126A

Across TCGA patient cohorts, TMEM126A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM126A-associated genes across cancer lineages are Mast cells, MEP, and pDC. Each is linked with TMEM126A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM126A-to-partner and partner-to-TMEM126A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mast cells grouped by TMEM126A-low versus TMEM126A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM126A→partner) and Y-score (partner→TMEM126A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mast cells →	+0.022	+2.850	.024	.035	3	1
UCEC	MEP →	+0.053	+2.818	.001	.037	3	1
UCEC	pDC →	+0.116	+2.818	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mast cells by TMEM126A expression — UCEC

Explore this box plot interactively →