TMEM123

Across TCGA patient cohorts, TMEM123 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,394 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM123-associated proteins across cancer lineages are ST14, REXO2, and PGM2L1. Each is linked with TMEM123 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM123-to-partner and partner-to-TMEM123 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM123 versus ST14 in OV, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM123→partner) and Y-score (partner→TMEM123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ST14 →	+0.540	+1.037	<.001	<.001	3	5
BRCA	REXO2 →	+0.316	+0.622	<.001	<.001	3	3
LSCC	PGM2L1 →	+0.487	+0.492	.004	.003	2	4
PDAC	YAP1_S164 →	+0.659	+0.466	.001	<.001	3	3
BRCA	CBX4_S291 →	-0.657	-0.778	<.001	<.001	3	3
BRCA	YAP1 →	+0.382	+1.142	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,394 associations by consensus.

TMEM123 vs ST14 — OV

Explore this scatter interactively →