TMEM123

Across TCGA cell cohorts, TMEM123 protein abundance is significantly associated with the RNA expression of many other genes, with 3,194 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM123-associated genes across cancer lineages are BIRC2, ETS1, and CWF19L2. Each is linked with TMEM123 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM123-to-partner and partner-to-TMEM123 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM123 versus BIRC2 in OVARY, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM123→partner) and Y-score (partner→TMEM123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	BIRC2 →	+1.324	+1.578	<.001	.001	3	8
BONE	ETS1 →	+5.172	+2.769	<.001	.004	3	8
STOMACH	CWF19L2 →	+0.825	+1.445	.006	.007	2	9
LARGE_INTESTINE	YAP1 →	+1.415	+2.224	<.001	<.001	3	7
OVARY	C11orf68 →	+1.346	+1.330	<.001	.004	3	7
LUNG_NSCLC_LUAD	ATL3 →	+0.743	+0.953	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,194 associations by consensus.

TMEM123 vs BIRC2 — OVARY

Explore this scatter interactively →