Across TCGA cell cohorts, TMEM121 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,238 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TMEM121-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Negative regulation of calcium ion export across plasma membrane, and ATP metabolic process. Each is linked with TMEM121 in more than 15 cancer types. Because this analysis shows association rather than direction, both TMEM121-to-partner and partner-to-TMEM121 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM121→partner) and Y-score (partner→TMEM121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleoside triphosphate metabolic process →	+0.131	+1.888	.001	<.001	3	16
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.082	+1.340	<.001	<.001	3	15
OESOPHAGUS	ATP metabolic process →	+0.108	+1.333	.004	.004	3	15
BONE	Purine nucleoside triphosphate metabolic process →	+0.101	+1.088	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.121	+0.770	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.184	+1.009	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,238 associations by consensus.

Exploration

TMEM121 survival (RNA) · tumor vs normal (RNA) · all TMEM121 data types