Across TCGA patient cohorts, TMEM120B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,583 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM120B-associated proteins across cancer lineages are PRPF31, PRPF4, and PRPF6. Each is linked with TMEM120B in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM120B-to-partner and partner-to-TMEM120B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120B→partner) and Y-score (partner→TMEM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRPF31 →	+0.302	+0.323	<.001	<.001	3	4
GBM	PRPF4 →	+0.323	+0.552	<.001	<.001	3	4
GBM	PRPF6 →	+0.312	+0.340	<.001	<.001	3	4
LSCC	RBM19 →	+0.400	+0.449	<.001	<.001	2	5
LSCC	MTREX →	+0.256	+0.442	<.001	<.001	3	4
LSCC	NLE1 →	+0.311	+0.295	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,583 associations by consensus.

Exploration

TMEM120B survival (RNA) · tumor vs normal (RNA) · all TMEM120B data types