Across TCGA patient cohorts, TMEM120B protein abundance is significantly associated with the RNA expression of many other genes, with 2,207 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM120B-associated genes across cancer lineages are SLC39A1, RNU6-728P, and SRSF9. Each is linked with TMEM120B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM120B-to-partner and partner-to-TMEM120B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120B→partner) and Y-score (partner→TMEM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC39A1 →	-0.363	-0.345	.004	.003	3	2
CCRCC	RNU6-728P →	+0.305	+0.449	<.001	<.001	3	2
BRCA	SRSF9 →	+0.511	+0.572	<.001	<.001	3	2
PDAC	PBX1 →	+0.440	+0.386	.003	.008	3	2
PDAC	PBX1-AS1 →	+0.452	+0.449	.003	.002	3	2
CCRCC	OR6M3P →	+0.175	+0.472	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,207 associations by consensus.

Exploration

TMEM120B survival (RNA) · tumor vs normal (RNA) · all TMEM120B data types