Across TCGA cell cohorts, TMEM120B RNA expression is significantly associated with the RNA expression of many other genes, with 11,466 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TMEM120B-associated genes across cancer lineages are DDX55, GCN1, and ATXN2. Each is linked with TMEM120B in more than 15 cancer types. Because this analysis shows association rather than direction, both TMEM120B-to-partner and partner-to-TMEM120B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120B→partner) and Y-score (partner→TMEM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DDX55 →	+0.886	+0.697	<.001	<.001	3	16
KIDNEY	GCN1 →	+1.009	+1.059	<.001	<.001	3	16
BONE	ATXN2 →	+0.852	+0.881	<.001	<.001	3	14
BONE	HECTD4 →	+1.383	+0.792	<.001	<.001	3	14
KIDNEY	BAZ2A →	+1.337	+0.974	.001	<.001	3	14
BONE	DDX51 →	+1.172	+0.917	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,466 associations by consensus.

Exploration

TMEM120B survival (RNA) · tumor vs normal (RNA) · all TMEM120B data types