TMEM104

Across TCGA patient cohorts, TMEM104 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,464 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM104-associated proteins across cancer lineages are TXNDC9, MAST4_S1523, and NPLOC4. Each is linked with TMEM104 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM104-to-partner and partner-to-TMEM104 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM104 versus TXNDC9 in UCEC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM104→partner) and Y-score (partner→TMEM104) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TXNDC9 →	+0.222	+0.552	.003	.005	3	4
LUAD	MAST4_S1523 →	-0.647	-0.545	<.001	<.001	3	4
OV	NPLOC4 →	+0.170	+0.525	.008	.005	2	5
UCEC	JPT1 →	+0.533	+0.712	<.001	<.001	3	4
PDAC	PURA →	-0.221	-0.259	.001	<.001	3	4
COAD	ARHGEF37 →	-0.341	-0.420	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,464 associations by consensus.

TMEM104 vs TXNDC9 — UCEC

Explore this scatter interactively →