TMEM102

Across TCGA cell cohorts, TMEM102 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,542 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM102-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Endosomal transport, and T cell mediated cytotoxicity. Each is linked with TMEM102 in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM102-to-partner and partner-to-TMEM102 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by TMEM102-low versus TMEM102-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM102→partner) and Y-score (partner→TMEM102) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytotoxic T cell degranulation →	+0.249	+1.087	.001	.002	3	13
LUNG_SCLC	Endosomal transport →	+0.053	+1.550	<.001	<.001	3	10
OVARY	T cell mediated cytotoxicity →	+0.199	+0.945	.002	.001	3	9
SOFT_TISSUE	T cell mediated immunity →	+0.143	+0.707	<.001	.001	3	9
STOMACH	Negative regulation of supramolecular fiber organization →	+0.077	+0.962	<.001	<.001	3	9
STOMACH	Desmosome organization →	+0.377	+0.981	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,542 associations by consensus.

Cytotoxic T cell degranulation by TMEM102 expression — STOMACH

Explore this box plot interactively →