TMEM101

Across TCGA patient cohorts, TMEM101 mutation is significantly associated with the RNA expression of many other genes, with 1,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM101-associated genes across cancer lineages are MIR4507, MIR4510, and RPS12P15. Each is linked with TMEM101 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM101-to-partner and partner-to-TMEM101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4507 grouped by TMEM101-low versus TMEM101-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM101→partner) and Y-score (partner→TMEM101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4507 →	+0.581	+3.705	<.001	.008	3	2
CESC	MIR4510 →	+0.238	+4.757	<.001	.004	3	2
COAD	RPS12P15 →	+0.153	+4.693	<.001	.007	3	2
COAD	SMARCE1P4 →	+0.316	+5.221	.003	.001	3	2
UCEC	RNU6-97P →	+0.455	+1.559	.001	.007	3	2
LIHC	NDUFA8P1 →	+0.113	+5.108	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,209 associations by consensus.

MIR4507 by TMEM101 expression — CESC

Explore this box plot interactively →