TMEM101

Across TCGA cell cohorts, TMEM101 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,619 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM101-associated GO terms across cancer lineages are Negative regulation of respiratory burst involved in inflammatory response, Negative regulation of respiratory burst, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with TMEM101 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM101-to-partner and partner-to-TMEM101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of respiratory burst involved in inflammatory response grouped by TMEM101-low versus TMEM101-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM101→partner) and Y-score (partner→TMEM101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of respiratory burst involved in inflammatory response →	+0.094	+0.538	.001	<.001	3	7
LUNG_NSCLC_LUAD	Negative regulation of respiratory burst →	+0.094	+0.538	.001	<.001	3	7
STOMACH	Mitochondrial electron transport, cytochrome c to oxygen →	+0.099	+0.608	.001	.001	3	7
BREAST	Positive regulation of stress granule assembly →	+0.106	+1.969	.002	.001	3	7
BLOOD_Lymphoma	Endosomal lumen acidification →	+0.079	+0.560	.004	.004	3	7
BLOOD_Lymphoma	Regulation of intralumenal vesicle formation →	+0.203	+0.631	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,619 associations by consensus.

Negative regulation of respiratory burst involved in inflammatory response by TMEM101 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →