TMEM101

Across TCGA cell cohorts, TMEM101 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM101-associated genes across cancer lineages are LCN1, PRM3, and TMEM239. Each is linked with TMEM101 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM101-to-partner and partner-to-TMEM101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCN1 grouped by TMEM101-low versus TMEM101-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM101→partner) and Y-score (partner→TMEM101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LCN1 →	+0.030	+4.922	.002	.009	3	1
BLOOD_Leukemia	PRM3 →	+0.090	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	TMEM239 →	+0.086	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SPATA31A7 →	+0.038	+5.539	<.001	.003	3	1
LARGE_INTESTINE	STRA8 →	+0.215	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ZNF804B →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

LCN1 by TMEM101 expression — BLOOD_Leukemia

Explore this box plot interactively →