TMEM100

Across TCGA patient cohorts, TMEM100 protein abundance is significantly associated with the RNA expression of many other genes, with 1,965 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM100-associated genes across cancer lineages are EDNRB, BMP5, and TEK. Each is linked with TMEM100 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM100-to-partner and partner-to-TMEM100 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM100 versus EDNRB in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM100→partner) and Y-score (partner→TMEM100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EDNRB →	+0.838	+0.562	.001	.003	3	3
LSCC	BMP5 →	+1.319	+0.598	<.001	<.001	3	2
LSCC	TEK →	+0.697	+0.516	<.001	<.001	3	2
LSCC	FCN3 →	+1.417	+0.748	<.001	<.001	3	2
LSCC	DKK2 →	+0.467	+0.382	.006	.002	3	2
LSCC	CA4 →	+0.832	+0.489	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,965 associations by consensus.

TMEM100 vs EDNRB — GBM

Explore this scatter interactively →