TMEM100

Across TCGA cell cohorts, TMEM100 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,517 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TMEM100-associated GO terms across cancer lineages are Hippocampus development, Regulation of sodium ion transport, and Establishment of skin barrier. Each is linked with TMEM100 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM100-to-partner and partner-to-TMEM100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hippocampus development grouped by TMEM100-low versus TMEM100-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM100→partner) and Y-score (partner→TMEM100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Hippocampus development →	+0.095	+0.053	<.001	.002	3	5
OVARY	Regulation of sodium ion transport →	-0.079	-2.334	<.001	.003	3	5
SKIN	Establishment of skin barrier →	-0.170	-1.287	<.001	.001	3	5
OVARY	Skin epidermis development →	-0.106	-2.753	.003	.009	3	5
SKIN	Epigenetic regulation of gene expression →	+0.030	+1.343	<.001	<.001	3	5
BREAST	snRNA metabolic process →	+0.062	+0.290	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,517 associations by consensus.

Hippocampus development by TMEM100 expression — PANCREAS

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