TMEM100

Across TCGA cell cohorts, TMEM100 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM100-associated genes across cancer lineages are MAGEB4. Each is linked with TMEM100 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM100-to-partner and partner-to-TMEM100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by TMEM100-low versus TMEM100-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM100→partner) and Y-score (partner→TMEM100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MAGEB4 by TMEM100 expression — LARGE_INTESTINE

Explore this box plot interactively →