Across TCGA patient cohorts, TMED9 mutation is significantly associated with the RNA expression of many other genes, with 569 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMED9-associated genes across cancer lineages are MTND2P20, IMMP1L, and COX15. Each is linked with TMED9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMED9-to-partner and partner-to-TMED9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED9→partner) and Y-score (partner→TMED9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTND2P20 →	+0.164	+5.044	<.001	.009	3	2
UCEC	IMMP1L →	+0.432	+4.010	.004	<.001	3	1
UCEC	COX15 →	+0.401	+3.467	.009	.002	3	1
UCEC	EI24 →	+0.536	+2.906	.002	.002	3	1
UCEC	CHEK1 →	+0.581	+3.191	.009	.009	3	1
UCEC	CWC15 →	+0.412	+2.906	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 569 associations by consensus.

Exploration

TMED9 survival (RNA) · tumor vs normal (RNA) · all TMED9 data types