Across TCGA patient cohorts, TMED9 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMED9-associated genes across cancer lineages are JNK_pT183_Y185, Ku80, and p62 Lck ligand. Each is linked with TMED9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMED9-to-partner and partner-to-TMED9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED9→partner) and Y-score (partner→TMED9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.195	-2.571	.013	.011	3	1
UCEC	Ku80 →	+0.234	+1.887	.033	.031	3	1
UCEC	p62 Lck ligand →	+0.387	+3.331	.010	.005	3	1
UCEC	RBM15 →	+0.318	+2.598	.032	.006	3	1
UCEC	Smad3 →	+0.149	+2.584	.034	.011	3	1
UCEC	Bak →	+0.281	+2.321	.016	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

TMED9 survival (RNA) · tumor vs normal (RNA) · all TMED9 data types