TMED8

Across TCGA patient cohorts, TMED8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,933 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMED8-associated genes across cancer lineages are UBR7, LIN52, and VTI1B. Each is linked with TMED8 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMED8-to-partner and partner-to-TMED8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED8 versus UBR7 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED8→partner) and Y-score (partner→TMED8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBR7 →	+0.566	+0.301	<.001	<.001	3	6
LUAD	LIN52 →	+0.479	+0.265	<.001	<.001	3	6
LUAD	VTI1B →	+0.339	+0.217	<.001	.001	3	5
BRCA	SAMD15 →	+1.039	+0.402	<.001	<.001	3	5
GBM	SPTLC2 →	+0.582	+0.317	<.001	<.001	3	5
BRCA	DICER1 →	+0.461	+0.267	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,933 associations by consensus.

TMED8 vs UBR7 — BRCA

Explore this scatter interactively →