TMED7

Across TCGA cell cohorts, TMED7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,418 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMED7-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Regulation of protein exit from endoplasmic reticulum, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with TMED7 in more than 17 cancer types. Because this analysis shows association rather than direction, both TMED7-to-partner and partner-to-TMED7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by TMED7-low versus TMED7-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED7→partner) and Y-score (partner→TMED7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of protein exit from endoplasmic reticulum →	+0.129	+0.953	.001	<.001	3	18
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.141	+1.372	<.001	<.001	3	16
BLOOD_Myeloma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.070	+0.914	.001	.001	2	15
BONE	COPII-coated vesicle cargo loading →	+0.153	+1.416	<.001	<.001	3	14
BLOOD_Myeloma	Endoplasmic reticulum organization →	+0.092	+0.875	.006	.003	3	14
BONE	Endoplasmic reticulum to cytosol transport →	+0.128	+1.244	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,418 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by TMED7 expression — KIDNEY

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