TMED7-TICAM2

Across TCGA patient cohorts, TMED7-TICAM2 mutation is significantly associated with the RNA expression of many other genes, with 2,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMED7-TICAM2-associated genes across cancer lineages are RNU6-670P, RNU6-756P, and MIR626. Each is linked with TMED7-TICAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMED7-TICAM2-to-partner and partner-to-TMED7-TICAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-670P grouped by TMED7-TICAM2-low versus TMED7-TICAM2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED7-TICAM2→partner) and Y-score (partner→TMED7-TICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-670P →	+0.489	+5.273	<.001	.006	3	1
LUSC	RNU6-756P →	+0.494	+5.978	<.001	.002	3	1
LUSC	MIR626 →	+0.512	+5.273	<.001	.006	3	1
LUSC	MIR605 →	+0.559	+6.191	<.001	.001	3	1
LUSC	RNA5SP511 →	+0.461	+5.474	<.001	.005	3	1
LUSC	RPS26P30 →	+0.258	+5.038	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,308 associations by consensus.

RNU6-670P by TMED7-TICAM2 expression — LUSC

Explore this box plot interactively →