TMED6

Across TCGA patient cohorts, TMED6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,060 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMED6-associated proteins across cancer lineages are RBM47, TAF12_S51, and PARN. Each is linked with TMED6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMED6-to-partner and partner-to-TMED6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED6 versus RBM47 in CCRCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED6→partner) and Y-score (partner→TMED6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RBM47 →	+0.264	+0.671	<.001	.001	3	3
LUAD	TAF12_S51 →	-0.611	-0.616	.001	<.001	3	3
LUAD	PARN →	+0.231	+0.634	<.001	<.001	3	3
UCEC	PBLD →	+0.659	+0.769	<.001	<.001	3	3
PDAC	SIPA1 →	-0.246	-0.745	<.001	.003	3	3
UCEC	IGHG1 →	-0.646	-0.576	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,060 associations by consensus.

TMED6 vs RBM47 — CCRCC

Explore this scatter interactively →