TMED5

Across TCGA cell cohorts, TMED5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,880 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMED5-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Cytosol to Golgi apparatus transport, and Regulation of protein exit from endoplasmic reticulum. Each is linked with TMED5 in more than 16 cancer types. Because this analysis shows association rather than direction, both TMED5-to-partner and partner-to-TMED5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by TMED5-low versus TMED5-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED5→partner) and Y-score (partner→TMED5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Zinc ion import into Golgi lumen →	+0.138	+0.820	<.001	<.001	3	17
STOMACH	Cytosol to Golgi apparatus transport →	+0.118	+0.929	<.001	.003	2	14
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.120	+0.836	.003	.002	3	12
BONE	Response to hepatocyte growth factor →	+0.180	+0.975	<.001	<.001	3	12
LUNG_SCLC	UDP-galactose transmembrane transport →	+0.137	+0.683	.001	.002	3	11
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.129	+0.896	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

Zinc ion import into Golgi lumen by TMED5 expression — KIDNEY

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