TMED3

Across TCGA patient cohorts, TMED3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,090 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMED3-associated genes across cancer lineages are CKAP4, PPIB, and PPIC. Each is linked with TMED3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMED3-to-partner and partner-to-TMED3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED3 versus CKAP4 in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED3→partner) and Y-score (partner→TMED3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CKAP4 →	+0.510	+0.316	.001	.009	3	6
LUAD	PPIB →	+0.548	+0.407	<.001	<.001	3	5
BRCA	PPIC →	+0.586	+0.296	<.001	.001	3	4
GBM	LOXL1 →	+0.932	+0.415	<.001	.001	3	4
LSCC	SEC24D →	+0.408	+0.265	<.001	<.001	3	4
LSCC	RPN2 →	+0.410	+0.316	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,090 associations by consensus.

TMED3 vs CKAP4 — BRCA

Explore this scatter interactively →