TMED2

Across TCGA patient cohorts, TMED2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,577 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMED2-associated genes across cancer lineages are EXOSC3, GARNL3, and SRSF7. Each is linked with TMED2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMED2-to-partner and partner-to-TMED2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED2 versus EXOSC3 in LSCC, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED2→partner) and Y-score (partner→TMED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EXOSC3 →	-0.437	-0.153	.002	.007	3	5
LSCC	GARNL3 →	-0.543	-0.235	<.001	<.001	3	5
LSCC	SRSF7 →	-0.439	-0.159	<.001	.006	3	4
OV	TTF1 →	-0.602	-0.382	<.001	<.001	3	4
GBM	PPP1R16B →	-1.091	-0.246	<.001	<.001	3	4
LSCC	SMC3 →	-0.603	-0.185	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,577 associations by consensus.

TMED2 vs EXOSC3 — LSCC

Explore this scatter interactively →