TMED2

Across TCGA patient cohorts, TMED2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMED2-associated genes across cancer lineages are CD4+ Tcm, Erythrocytes, and Sebocytes. Each is linked with TMED2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMED2-to-partner and partner-to-TMED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by TMED2-low versus TMED2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED2→partner) and Y-score (partner→TMED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CD4+ Tcm →	+0.085	+4.527	<.001	.017	3	1
UCEC	Erythrocytes →	+0.023	+2.818	.044	.035	3	1
UCEC	Sebocytes →	-0.031	-2.916	.007	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tcm by TMED2 expression — BLCA

Explore this box plot interactively →