TMED2

Across TCGA cell cohorts, TMED2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,214 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMED2-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and ERAD pathway. Each is linked with TMED2 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMED2-to-partner and partner-to-TMED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by TMED2-low versus TMED2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED2→partner) and Y-score (partner→TMED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endoplasmic reticulum to cytosol transport →	+0.141	+0.610	.002	.009	2	14
OESOPHAGUS	Retrograde protein transport, ER to cytosol →	+0.141	+0.610	.002	.009	2	14
BLOOD_Myeloma	ERAD pathway →	+0.088	+0.857	<.001	<.001	3	11
BLOOD_Myeloma	Endoplasmic reticulum mannose trimming →	+0.103	+0.914	.003	<.001	3	11
BREAST	Golgi vesicle transport →	+0.066	+0.804	<.001	<.001	3	11
OESOPHAGUS	Phospholipid biosynthetic process →	+0.050	+0.578	.002	.006	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,214 associations by consensus.

Endoplasmic reticulum to cytosol transport by TMED2 expression — OESOPHAGUS

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