TMED2

Across TCGA cell cohorts, TMED2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,868 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMED2-associated genes across cancer lineages are FOXO4, SNTA1, and KLF4. Each is linked with TMED2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMED2-to-partner and partner-to-TMED2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED2 versus FOXO4 in LUNG_SCLC, with a Pearson correlation of -0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED2→partner) and Y-score (partner→TMED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FOXO4 →	-1.286	-3.205	.003	<.001	3	3
LUNG_NSCLC_LUAD	SNTA1 →	+1.426	+1.960	.005	.009	3	2
LUNG_SCLC	KLF4 →	-4.151	-4.316	.006	<.001	3	2
LUNG_NSCLC_LUAD	CBLC →	-3.807	-1.947	.002	.002	3	2
LUNG_NSCLC_LUAD	SOX13 →	-1.992	-1.397	.002	.007	3	2
LUNG_NSCLC_LUAD	LRRC14 →	-1.370	-1.835	.007	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,868 associations by consensus.

TMED2 vs FOXO4 — LUNG_SCLC

Explore this scatter interactively →