TMED1

Across TCGA patient cohorts, TMED1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,440 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMED1-associated genes across cancer lineages are CNIH3, STYK1, and CCDC130. Each is linked with TMED1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMED1-to-partner and partner-to-TMED1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMED1 versus CNIH3 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED1→partner) and Y-score (partner→TMED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNIH3 →	+0.674	+0.313	<.001	<.001	3	4
UCEC	STYK1 →	-0.864	-0.496	.001	<.001	3	4
OV	CCDC130 →	+0.600	+0.449	.002	.001	3	4
OV	TYK2 →	+1.036	+0.602	<.001	<.001	3	4
OV	FBXL12 →	+0.760	+0.613	.001	<.001	3	4
OV	PRKCSH →	+1.017	+0.560	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,440 associations by consensus.

TMED1 vs CNIH3 — GBM

Explore this scatter interactively →