TMED1

Across TCGA cell cohorts, TMED1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,091 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMED1-associated GO terms across cancer lineages are Protein insertion into ER membrane, Positive regulation of lysosomal protein catabolic process, and Glycoprotein biosynthetic process. Each is linked with TMED1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TMED1-to-partner and partner-to-TMED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane grouped by TMED1-low versus TMED1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED1→partner) and Y-score (partner→TMED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein insertion into ER membrane →	+0.090	+0.658	.004	.004	3	13
CNS	Positive regulation of lysosomal protein catabolic process →	+0.167	+0.564	<.001	.002	3	12
LUNG_NSCLC_LUAD	Glycoprotein biosynthetic process →	+0.039	+0.702	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.048	+0.849	.001	<.001	3	11
BONE	Viral process →	+0.079	+0.862	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of protein folding →	+0.128	+0.905	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,091 associations by consensus.

Protein insertion into ER membrane by TMED1 expression — BONE

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