TMCO6

Across TCGA patient cohorts, TMCO6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,628 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMCO6-associated proteins across cancer lineages are GEMIN5, HNRNPA0, and KAT8. Each is linked with TMCO6 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMCO6-to-partner and partner-to-TMCO6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMCO6 versus GEMIN5 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO6→partner) and Y-score (partner→TMCO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GEMIN5 →	+0.282	+0.427	<.001	<.001	3	6
OV	HNRNPA0 →	+0.386	+0.444	<.001	<.001	3	5
LSCC	KAT8 →	+0.213	+0.351	<.001	<.001	3	5
LSCC	KDM3B →	+0.290	+0.564	<.001	<.001	3	5
LSCC	RRBP1 →	-0.425	-0.527	<.001	<.001	3	5
LSCC	SMC1A →	+0.187	+0.361	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,628 associations by consensus.

TMCO6 vs GEMIN5 — LSCC

Explore this scatter interactively →