TMCO6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMCO6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMCO6-associated genes across cancer lineages are LINC01147, CSGALNACT1, and FREM2. Each is linked with TMCO6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMCO6-to-partner and partner-to-TMCO6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMCO6 versus LINC01147 in LSCC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO6→partner) and Y-score (partner→TMCO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCLINC01147 →-0.494-0.289.001.00133
BRCACSGALNACT1 →-0.764-0.543<.001<.00132
HNSCFREM2 →-1.245-0.327.005.00632
LSCCRPS2P7 →+0.846+0.301<.001.00432
COADEIF3B →+0.542+0.483.004.00132
COADPRPF19 →+0.682+0.536.005.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,006 associations by consensus.

TMCO6 vs LINC01147 — LSCC

Per-sample scatter of TMCO6 vs LINC01147 in LSCC (Pearson r = -0.32).

Explore this scatter interactively →

Exploration