TMCO3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMCO3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,487 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMCO3-associated proteins across cancer lineages are CUL4A, TPP2, and LAMP1. Each is linked with TMCO3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMCO3-to-partner and partner-to-TMCO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMCO3 versus CUL4A in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO3→partner) and Y-score (partner→TMCO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCUL4A →+0.410+0.643.002.00137
OVTPP2 →+0.335+0.852.002<.00136
LSCCLAMP1 →+0.635+0.811<.001<.00135
OVTUBGCP3 →+0.273+0.855<.001<.00134
HNSCIRF4 →-0.761-0.432<.001.00434
COADMRPL15 →-0.289-0.534.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,487 associations by consensus.

TMCO3 vs CUL4A — OV

Per-sample scatter of TMCO3 vs CUL4A in OV (Pearson r = 0.42).

Explore this scatter interactively →

Exploration