TMCO3

Across TCGA cell cohorts, TMCO3 mutation is significantly associated with the drug of many other genes, with 43 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMCO3-associated genes across cancer lineages are CCT007093, Fulvestrant, and SGC-CBP30. Each is linked with TMCO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMCO3-to-partner and partner-to-TMCO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT007093 grouped by TMCO3-low versus TMCO3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO3→partner) and Y-score (partner→TMCO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCT007093 →	+0.355	+2.871	.011	.021	3	1
LARGE_INTESTINE	Fulvestrant →	+0.331	+2.871	.034	.021	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.344	+2.871	.009	.021	3	1
LARGE_INTESTINE	CDK9_5576 →	+0.530	+2.871	.032	.021	3	1
LARGE_INTESTINE	WYE-125132 →	+0.584	+2.652	.021	.045	3	1
LARGE_INTESTINE	kb NB 142-70 →	+0.539	+2.652	.022	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

CCT007093 by TMCO3 expression — LARGE_INTESTINE

Explore this box plot interactively →