Across TCGA patient cohorts, TMCO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,659 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMCO2-associated GO terms across cancer lineages are Regulation of DNA strand elongation, U2-type prespliceosome assembly, and Negative regulation of RNA splicing. Each is linked with TMCO2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TMCO2-to-partner and partner-to-TMCO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO2→partner) and Y-score (partner→TMCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA strand elongation →	+0.068	+0.259	<.001	<.001	3	15
STAD	U2-type prespliceosome assembly →	+0.079	+0.280	<.001	<.001	3	15
ESCA	Negative regulation of RNA splicing →	+0.089	+0.260	<.001	<.001	3	15
ESCA	Nucleolar large rRNA transcription by RNA polymerase I →	+0.064	+0.288	.001	<.001	3	15
STAD	Protein-RNA complex organization →	+0.066	+0.288	<.001	<.001	3	14
ESCA	Mitochondrial gene expression →	+0.079	+0.261	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,659 associations by consensus.

Exploration

TMCO2 survival (RNA) · tumor vs normal (RNA) · all TMCO2 data types