TMCC3

Across TCGA patient cohorts, TMCC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,505 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMCC3-associated proteins across cancer lineages are TMCC3_S242, TMCC3_T176, and TMCC3_T194. Each is linked with TMCC3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMCC3-to-partner and partner-to-TMCC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMCC3 versus TMCC3_S242 in OV, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCC3→partner) and Y-score (partner→TMCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TMCC3_S242 →	+1.375	+0.849	<.001	<.001	3	6
PDAC	TMCC3_T176 →	+0.799	+0.410	.001	.004	3	6
UCEC	TMCC3_T194 →	+1.105	+0.636	<.001	.001	3	6
HNSC	TMCC3_S46 →	+1.016	+0.510	<.001	<.001	3	5
LUAD	TMCC3_S4 →	+1.254	+0.754	<.001	.006	2	5
LSCC	LPCAT2 →	+0.379	+0.335	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,505 associations by consensus.

TMCC3 vs TMCC3_S242 — OV

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