TMCC2

Across TCGA cell cohorts, TMCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,417 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMCC2-associated GO terms across cancer lineages are Cytoplasmic translation, Nucleoside triphosphate metabolic process, and Heterochromatin formation. Each is linked with TMCC2 in more than 12 cancer types. Because this analysis shows association rather than direction, both TMCC2-to-partner and partner-to-TMCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by TMCC2-low versus TMCC2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCC2→partner) and Y-score (partner→TMCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cytoplasmic translation →	+0.096	+1.044	.002	.003	3	13
OESOPHAGUS	Nucleoside triphosphate metabolic process →	+0.137	+1.429	<.001	<.001	3	13
LARGE_INTESTINE	Heterochromatin formation →	+0.071	+0.884	<.001	.005	3	12
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.124	+1.326	<.001	<.001	3	12
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.181	+1.446	<.001	.002	3	12
STOMACH	Regulation of cell cycle G1/S phase transition →	+0.069	+1.761	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,417 associations by consensus.

Cytoplasmic translation by TMCC2 expression — OESOPHAGUS

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