TMCC2

Across TCGA cell cohorts, TMCC2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,698 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMCC2-associated GO terms across cancer lineages are Modification of synaptic structure, Positive regulation of muscle cell differentiation, and Regulation of biological process involved in symbiotic interaction. Each is linked with TMCC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMCC2-to-partner and partner-to-TMCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modification of synaptic structure grouped by TMCC2-low versus TMCC2-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCC2→partner) and Y-score (partner→TMCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Modification of synaptic structure →	+0.074	+0.774	.007	.006	3	6
SOFT_TISSUE	Positive regulation of muscle cell differentiation →	-0.115	-1.072	<.001	.005	3	5
BLOOD_Lymphoma	Regulation of biological process involved in symbiotic interaction →	+0.125	+1.074	.004	.001	3	5
BLOOD_Lymphoma	Nuclear receptor-mediated signaling pathway →	+0.058	+1.164	.004	.003	3	5
CNS	Viral life cycle →	+0.060	+0.704	<.001	<.001	3	5
CNS	Biological process involved in symbiotic interaction →	+0.085	+0.710	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,698 associations by consensus.

Modification of synaptic structure by TMCC2 expression — LARGE_INTESTINE

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