Across TCGA pan-cancer cohorts, TMCC1P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TMCC1P1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where TMCC1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMCC1P1 is over-expressed in tumor.
COAD are the cancer types where TMCC1P1 tumor–normal differential expression is most reproducible.