TMCC1

Across TCGA cell cohorts, TMCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,063 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMCC1-associated GO terms across cancer lineages are Endosome fission, Endosomal transport, and Protein polyubiquitination. Each is linked with TMCC1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TMCC1-to-partner and partner-to-TMCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome fission grouped by TMCC1-low versus TMCC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCC1→partner) and Y-score (partner→TMCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Endosome fission →	+0.181	+1.144	<.001	<.001	3	17
STOMACH	Endosomal transport →	+0.075	+1.159	<.001	<.001	3	11
STOMACH	Protein polyubiquitination →	+0.046	+0.759	.001	.002	3	11
STOMACH	Cellular response to nutrient levels →	+0.080	+1.221	<.001	<.001	3	10
STOMACH	Regulation of TOR signaling →	+0.058	+0.875	.009	.001	3	10
CNS	Negative regulation of macroautophagy →	+0.059	+0.578	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,063 associations by consensus.

Endosome fission by TMCC1 expression — BREAST

Explore this box plot interactively →