TMC7

Across TCGA patient cohorts, TMC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,282 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMC7-associated proteins across cancer lineages are TMC7_S72, ACOT7, and MYO9B. Each is linked with TMC7 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMC7-to-partner and partner-to-TMC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMC7 versus TMC7_S72 in BRCA, with a Pearson correlation of 0.94.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMC7→partner) and Y-score (partner→TMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMC7_S72 →	+2.700	+2.120	.005	.002	3	6
PDAC	ACOT7 →	+0.504	+0.598	<.001	<.001	3	4
CCRCC	MYO9B →	-0.185	-0.294	.006	.004	3	3
CCRCC	ARHGAP30 →	-0.317	-0.288	.005	.003	3	3
LSCC	BTK →	-0.420	-0.467	.002	.006	3	3
LSCC	CD38 →	-0.812	-0.570	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,282 associations by consensus.

TMC7 vs TMC7_S72 — BRCA

Explore this scatter interactively →